Discovery of 4-(phenoxymethyl)-1H-1,2,3-triazole derivatives as novel xanthine oxidase inhibitors
Tingjian Zhang, Yi Zhang, Zhen-hao Zhang, Zhaoran Wang, Xu Zhang, Sen-sen Hu, Pengfei Lu, Shuai Guo, Fan‐hao Meng
Topics & Concepts
ChemistryXanthine oxidaseAllopurinolDocking (animal)StereochemistryUric acidTriazoleIn vivoIC501,2,4-TriazoleCombinatorial chemistryEnzyme inhibitorPharmacologyEnzymeIn vitroBiochemistryMedicinal chemistryOrganic chemistryPathologyNursingMedicineBiotechnologyBiologyGout, Hyperuricemia, Uric AcidEosinophilic Disorders and SyndromesCase Reports on Hematomas