Litcius/Paper detail

Anti-tumor effects of Skp2 inhibitor AAA-237 on NSCLC by arresting cell cycle at G0/G1 phase and inducing senescence

Jinyi Liu, Xiangjin Zheng, Li Wan, Liwen Ren, Sha Li, Yihui Yang, Hong Yang, Binbin Ge, Guanhua Du, Jianyou Shi, Jinhua Wang

2022Pharmacological Research29 citationsDOI

Topics & Concepts

SKP2SenescenceCell cycleApoptosisCancer researchLung cancerOncogeneCell cycle checkpointCancerG1 phaseCell growthMedicineBiologyInternal medicineUbiquitinBiochemistryUbiquitin ligaseGeneFOXO transcription factor regulationRNA modifications and cancerCancer-related Molecular Pathways