Melatonin exerts a protective effect in ameliorating nephrolithiasis via targeting AMPK/PINK1-Parkin mediated mitophagy and inhibiting ferroptosis in vivo and in vitro
Jiawei Zhou, Lingchao Meng, Ziqi He, Qianlin Song, Junwei Liu, Xiaozhe Su, Chuan Wang, Ke Hu, Caitao Dong, Wenbiao Liao, Sixing Yang
Topics & Concepts
MitophagyParkinMelatoninPINK1AMPKOxidative stressKidneyGene knockdownAutophagyEndocrinologyCell biologyInternal medicineBiologyMedicineApoptosisKinaseProtein kinase ABiochemistryDiseaseParkinson's diseaseDialysis and Renal Disease ManagementAutophagy in Disease and TherapyChronic Kidney Disease and Diabetes