Susceptibility of livestock to SARS-CoV-2 infection
Angela M. Bosco‐Lauth, Audrey Walker, Lauren Guilbert, Stephanie Porter, Airn E. Hartwig, Emma McVicker, Helle Bielefeldt‐Ohmann, Richard A. Bowen
Abstract
We report pilot studies to evaluate the susceptibility of common domestic livestock (cattle, sheep, goat, alpaca, rabbit, and horse) to intranasal infection with SARS-CoV-2. None of the infected animals shed infectious virus via nasal, oral, or faecal routes, although viral RNA was detected in several animals. Further, neutralizing antibody titres were low or non-existent one month following infection. These results suggest that domestic livestock are unlikely to contribute to SARS-CoV-2 epidemiology.
Topics & Concepts
LivestockVirologyNasal administrationBiologyVirusSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Veterinary medicineMedicineInfectious disease (medical specialty)DiseaseInternal medicineEcologySARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections StudiesSARS-CoV-2 detection and testing