PARP inhibition synergizes with CD47 blockade to promote phagocytosis by tumor-associated macrophages in homologous recombination-proficient tumors
Yangyang Liu, Rui Xue, Xixi Duan, Xiaoping Shang, Ming Wang, Fazhan Wang, Linyu Zhu, Lijing Zhang, Xin Ge, Xianlan Zhao, Hongjun Guo, Zhihong Wang, Lindong Zhang, Xiang Gao, Airong Shen, Yuqiao Sheng, Zhihai Qin
Topics & Concepts
OlaparibCancer researchPARP inhibitorFlow cytometryIn vivoImmunotherapyTumor microenvironmentCancerMedicineImmune systemBiologyImmunologyPoly ADP ribose polymeraseInternal medicineTumor cellsPolymeraseBiochemistryBiotechnologyGenePARP inhibition in cancer therapyPhagocytosis and Immune RegulationCancer Immunotherapy and Biomarkers