HIF-1α-activated TMEM237 promotes hepatocellular carcinoma progression via the NPHP1/Pyk2/ERK pathway
Tianxiang Chen, Liang Wang, Chao Chen, Runtian Li, Ning Zhu, Runkun Liu, Yongshen Niu, Zhengtao Xiao, Hui Liu, Qingguang Liu, Kangsheng Tu
Topics & Concepts
Cancer researchMAPK/ERK pathwayBiologyTumor progressionTranscription factorHepatocellular carcinomaSignal transductionHypoxia-inducible factorsMetastasisPhosphorylationReporter geneCell biologyGene expressionGeneCancerBiochemistryGeneticsCancer, Hypoxia, and MetabolismMitochondrial Function and PathologyAngiogenesis and VEGF in Cancer