Cell Cycle Progression Influences Biofilm Formation in Saccharomyces cerevisiae 1308
Ying Jiang, Caice Liang, Wei Zhao, Tianpeng Chen, Bin Yu, Anqi Hou, Jiaqing Zhu, Tao Zhang, Qingguo Liu, Hanjie Ying, Dong Liu, Wenjun Sun, Yong Chen
Abstract
Immobilised fermentation can be achieved using biofilm resistance, resulting in improved fermentation efficiency and yield. The link between the cell cycle and biofilms deserves further study since reports are lacking in this area. This study showed that the ability of Saccharomyces cerevisiae to produce biofilm differed when cell cycle progression was altered. Further studies suggested that cell cycle regulatory genes influenced biofilm formation by regulating cell adhesion and polysaccharide formation. Findings related to cell cycle regulation of biofilm formation set the stage for biofilm in Saccharomyces cerevisiae and provide a theoretical basis for the development of a new method to improve biofilm-based industrial fermentation.