Looking deep into C–H functionalization: the synthesis and application of cyclopentadienyl and related metal catalysts
Guilherme A. M. Jardim, Renato L. Carvalho, Mateus P. Nunes, Luana A. Machado, Leandro D. Almeida, Karim A. Bahou, John F. Bower, Eufrânio N. da Silva Júnior
Abstract
Metal catalyzed C-H functionalization offers a versatile platform for methodology development and a wide variety of reactions now exist for the chemo- and site-selective functionalization of organic molecules. Cyclopentadienyl-metal (CpM) complexes of transition metals and their correlative analogues have found widespread application in this area, and herein we highlight several key applications of commonly used transition-metal Cp-type catalysts. In addition, an understanding of transition metal Cp-type catalyst synthesis is important, particularly where modifications to the catalyst structure are required for different applications, and a summary of this aspect is given.