Role of sanguinarine in regulating immunosuppression in a Lewis lung cancer mouse model
Bei Li, Yingbin Luo, Yixi Zhou, Jianchun Wu, Zhihong Fang, Yan Li
Abstract
T cells. SNG may reduce the immunosuppressive state induced by lung cancer by promoting cell differentiation and by inhibiting the immunosuppressive activity of MDSCs.
Topics & Concepts
Lewis lung carcinomaCancer researchMyeloid-derived Suppressor CellImmune systemCD8Tumor microenvironmentImmunologyCytotoxic T cellFOXP3BiologyCancerChemistryIn vitroMetastasisSuppressorGeneticsBiochemistryImmune cells in cancerNeuroinflammation and Neurodegeneration MechanismsImmune Cell Function and Interaction