Schisandrin B targets cannabinoid 2 receptor in Kupffer cell to ameliorate CCl4-induced liver fibrosis by suppressing NF-κB and p38 MAPK pathway
Hai-Qiao Wang, Zhong Wan, Qiqiang Zhang, Tong Su, Dan Yu, Fei Wang, Chao Zhang, Wei Li, Xu D, Hai Zhang
Topics & Concepts
MAPK/ERK pathwayPharmacologyHepatic stellate cellNF-κBSchisandra chinensisCCL4Cancer researchCannabinoid receptor type 2FibrosisIn vivoChemistrySignal transductionReceptorBiologyMedicineCannabinoid receptorPathologyBiochemistryAgonistTraditional Chinese medicineBiotechnologyCarbon tetrachlorideOrganic chemistryAlternative medicineGenomics, phytochemicals, and oxidative stressDrug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology