Dissolution Challenges Associated with the Surface pH of Drug Particles: Integration into Mechanistic Oral Absorption Modeling
Bart Hens, Nidhi Seegobin, Marival Bermejo, Yasuhiro Tsume, Nicola Clear, Mark McAllister, Gregory E. Amidon, Gregory E. Amidon, Gordon L. Amidon, Gordon L. Amidon
Topics & Concepts
DissolutionIbuprofenBioequivalenceDissolution testingChemistryChromatographyCalculatorPopulationDrugDispersion (optics)Physiologically based pharmacokinetic modellingPharmacokineticsAbsorption (acoustics)Particle sizeSolubilityIVIVCMaterials scienceWork (physics)Chemical engineeringProcess engineeringPharmacologyAnalytical Chemistry (journal)Intersection (aeronautics)Extended releaseDrug Solubulity and Delivery SystemsAdvanced Drug Delivery SystemsGinkgo biloba and Cashew Applications