MAPK pathway and SIRT1 are involved in the down-regulation of secreted osteopontin expression by genistein in metastatic cancer cells
Kitboklang Khongsti, Kuheli Biswas Das, Bidyadhar Das
Topics & Concepts
OsteopontinGenisteinGene knockdownMAPK/ERK pathwayChromatin immunoprecipitationTransfectionSmall interfering RNABiologyMolecular biologyActivator (genetics)Western blotCell biologyCell cultureSignal transductionGene expressionPromoterBiochemistryGeneImmunologyEndocrinologyGeneticsSirtuins and Resveratrol in MedicineBone and Dental Protein StudiesPhytoestrogen effects and research