VDAC1 balances mitophagy and apoptosis in leafhopper upon arbovirus infection
Qian Chen, Dongsheng Jia, Jiping Ren, Yu Cheng, Haibo Wu, Shude Guo, Tàiyún Wèi
Abstract
: double-stranded RNAs targeting Pns11; dsRNA: double-stranded RNA; EC: epithelia cell; GST: glutathione S-transferase; LAMP1: lysosomal associated membrane protein 1; Mito: mitochondrion; Mmg: middle midgut; MP, mitophagosome; PG, phagophore. padp: post-first access to diseased plants; PINK1: PTEN induced kinase 1; RGDV: rice gall dwarf virus; SQSTM1: sequestosome 1; TOMM20: translocase of outer mitochondrial membrane 20; TUNEL: terminal deoxynucleotidyl transferase dUTP nick end labeling; VDAC1: voltage dependent anion channel 1.
Topics & Concepts
MitophagyVDAC1BiologyCell biologyAutophagyMitochondrionFIS1PINK1Apoptosismitochondrial fusionBiochemistryMitochondrial DNABacterial outer membraneGeneEscherichia coliMosquito-borne diseases and controlAutophagy in Disease and TherapyPlant Virus Research Studies