Design, synthesis and biological evaluations of a series of Pyrido[1,2-a]pyrimidinone derivatives as novel selective FGFR inhibitors
Kai Ran, Jun Zeng, Guoquan Wan, Xiaojie He, Zhanzhan Feng, Xiang Wang, Wei Wei, Xiang Hu, Ningyu Wang, Zhihao Liu, Luoting Yu
Topics & Concepts
Fibroblast growth factor receptorChemistryKinaseCell growthPharmacologyCancer researchIn vitroCarcinogenesisApoptosisReceptorBiochemistryFibroblast growth factorBiologyGeneFibroblast Growth Factor ResearchKruppel-like factors researchEpigenetics and DNA Methylation