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Distribution of dietary protein intake in daily meals influences skeletal muscle hypertrophy via the muscle clock

Shinya Aoyama, Hyeon-Ki Kim, Rina Hirooka, Mizuho Tanaka, Takeru Shimoda, Hanako Chijiki, Shuichi Kojima, Keisuke Sasaki, Kengo Takahashi, Saneyuki Makino, Miku Takizawa, Masaki Takahashi, Yu Tahara, Shigeki Shimba, Kazuyuki Shinohara, Shigenobu Shibata

2021Cell Reports68 citationsDOIOpen Access PDF

Abstract

or muscle-specific Bmal1 knockout mice. Additionally, we examined the relationship between the distribution of proteins in meals and muscle functions, such as skeletal muscle index and grip strength in humans. Higher muscle functions were observed in subjects who ingested dietary proteins mainly at breakfast than at dinner. These data suggest that protein intake at breakfast may be better for the maintenance of skeletal muscle mass.

Topics & Concepts

Skeletal muscleMuscle hypertrophyMuscle proteinInternal medicineDietary proteinEndocrinologyDistribution (mathematics)SarcopeniaBiologyChemistryCell biologyMedicineMathematicsMathematical analysisMuscle metabolism and nutritionNutrition and Health in AgingDiet and metabolism studies
Distribution of dietary protein intake in daily meals influences skeletal muscle hypertrophy via the muscle clock | Litcius