Licochalcone A alleviates ferroptosis in doxorubicin-induced cardiotoxicity via the PI3K/AKT/MDM2/p53 pathway
Ganxiao Chen, Shunxiang Luo, Hongdou Guo, Jiayi Lin, Shanghua Xu
Topics & Concepts
Protein kinase BPI3K/AKT/mTOR pathwayPharmacologyGlutathioneViability assayReactive oxygen speciesChemistryOxidative stressDoxorubicinCardiotoxicityMalondialdehydeCancer researchBiochemistryMedicineSignal transductionCellToxicityInternal medicineEnzymeOrganic chemistryChemotherapyPharmacological Effects of Natural CompoundsHormonal Regulation and HypertensionFerroptosis and cancer prognosis