Litcius/Paper detail

Emphysema at Baseline Low-Dose CT Lung Cancer Screening Predicts Death from Chronic Obstructive Pulmonary Disease and Cardiovascular Disease Up to 25 Years Later

Jessica González, Rowena Yip, Javier J. Zulueta, Samuel M. Aguayo, Daniel M. Libby, Mark Pasmantier, David F. Yankelevitz, Claudia I. Henschke, for the International Early Lung Cancer Action Program Investigators, Claudia I. Henschke, David F. Yankelevitz, Rowena Yip, Artit Jirapatnakul, Raja M. Flores, Andrew Kaufman, Andrea Wolf, Daniel Nicastri, Timothy J. Harkin, Javier J. Zulueta, Emanuela Taioli, Anthony P. Reeves, Nasser K. Altorki, James P. Smith, Daniel M. Libby, Mark Pasmantier, Steven Markowitz, Albert Miller, José Cervera Deval, Dorith Shaham, Luis Seijo, Gorka Bastarika, Luis M. Montuenga, Cheryl Aylesworth, Karl Klingler, Othmar Schöb, Shahriyour Andaz, Michaela Straznicka, Cynthia Chin, Todd S. Weiser, Shusuke Sone, Takaomi Hanaoka, Heidi Roberts, Demetris Patsios, M. Scopetuolo, Andrew Brown, Thomas Bauer, Stefano Canitano, Salvatore Giunta, Ning Wu, Enser Cole, Patrick Meyers, Diana Yeh, Dan W. Luedke, Xueguo Liu, Gary Herzog, Ralph W. Aye, Matthew D. Rifkin, Giula Veronesi, Maurizio Infante, Davood Vafai, Samuel Kopel, Jana Taylor, Richard J. Thurer, Nestor Villamizar, John H. M. Austin, Gregory D. Pearson, Donald Klippenstein, Alan Litwin, Peter Loud, Leslie J. Kohman, Ernest M. Scalzetti, Arfa Khan, Rakesh Shah, William Mayfield, Carmine Frumiento, Michael V. Smith, M. Kristin Thorsen, Richard M. Hansen, David P. Naidich, Georgeann McGuinness, Mark Widmann, Robert J. Korst, J. Lowry, Mary Salvatore, James Walsh, David Bertsch, Paul Scheinberg, Barry Sheppard, G Cecchi, Michelle S. Ginsberg, Dennis Slater, Laura S. Welch, Fred Grannis, Arnold Rotter, Cliff P. Connery, Terence A.S. Matalon, Edson H. Cheung, Robert Glassberg, David K. Olsen, David Mullen

2025Radiology10 citationsDOIOpen Access PDF

Abstract

Emphysema identified at baseline low-dose CT in a lung cancer screening program was predictive of all-cause, chronic obstructive pulmonary disease, and cardiovascular disease mortality 25 years later in 9047 asymptomatic adults with a smoking history.

Topics & Concepts

MedicineCOPDInternal medicineAsymptomaticLung cancerProspective cohort studyCohortObstructive lung diseaseProportional hazards modelCause of deathDiseaseCohort studyLung cancer screeningRespiratory diseasePredictive value of testsMortality ratePulmonary diseaseCancerComorbidityRisk of mortalitySurgeryLungChronic Obstructive Pulmonary Disease (COPD) ResearchLung Cancer Diagnosis and TreatmentInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis