CuAAC-ensembled 1,2,3-triazole-linked isosteres as pharmacophores in drug discovery: review
A. Shobha Rani, Gurjaspreet Singh, Akshpreet Singh, Ubair Maqbool, Gurpreet Kaur, Jandeep Singh
Abstract
The review lays emphasis on the significance of 1,2,3-triazoles synthesized<italic>via</italic>CuAAC reaction having potential to act as anti-microbial, anti-cancer, anti-viral, anti-inflammatory, anti-tuberculosis, anti-diabetic, and anti-Alzheimer drugs.
Topics & Concepts
PharmacophoreTriazoleCombinatorial chemistryChemistryDrug discoveryStereochemistryDrugPharmacologyMedicineBiochemistryOrganic chemistryClick Chemistry and ApplicationsSynthesis and Biological EvaluationSynthesis and Catalytic Reactions