Decreased Risk of Coronavirus Disease 2019–Related Hospitalization Associated With the Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2
Jessica P. Ridgway, Samuel Tideman, Bill Wright, Ari Robicsek
Abstract
Among 134 223 patients with coronavirus disease 2019 (COVID-19), we assessed how risk of hospitalization changed at different intervals in the pandemic, controlling for prior COVID-19 immunity. In multivariable analysis, outpatients with COVID-19 during the Omicron-predominant time period had significantly lower odds of hospitalization compared to pre-Delta (adjusted odds ratio, 0.26 [95% confidence interval, .22-.32]).
Topics & Concepts
MedicineOdds ratioCoronavirus disease 2019 (COVID-19)Confidence intervalSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)CoronavirusPandemic2019-20 coronavirus outbreakInternal medicineOddsBetacoronavirusDiseaseVirologyLogistic regressionInfectious disease (medical specialty)OutbreakSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19