Different effects of <i>Bacillus coagulans</i> vegetative cells and spore isolates on constipation-induced gut microbiota dysbiosis in mice
Liuruolan Li, Bingshu Liu, Jiang Cao, Hao Zhang, Fengwei Tian, Leilei Yu, Wei Chen, Qixiao Zhai
Abstract
B. coagulans spore had higher survival rate in simulated GI environment than the corresponding vegetative cells. B. coagulans GBI-30 6086 and B. coagulans 90 spores relieve constipation by modulating the microbiota significantly associated with SCFA.
Topics & Concepts
Bacillus coagulansDysbiosisSporeEndosporeBiologyConstipationMicrobiologyBacillus (shape)Gut floraProbioticFood scienceBacteriaMedicineGastroenterologyImmunologyFermentationGeneticsGut microbiota and healthGastrointestinal motility and disordersProbiotics and Fermented Foods