Tumor-targeted AIE polymeric micelles mediated immunogenic sonodynamic therapy inhibits cancer growth and metastasis
Kai Deng, Yifeng Yu, Yong Zhao, Jia‐Mi Li, Kun‐Heng Li, Hongyang Zhao, Meng Wu, Shi‐Wen Huang
Abstract
by salicylaldazine for inhibiting neovascularization in tumor tissues. Ultimately, AIE/Biotin-M systemically inhibited tumor growth and metastasis upon US irradiation. This study presents a facile approach to the development of AIE nanosonosensitizers for cancer SDT.
Topics & Concepts
NanocarriersCancer researchImmunogenic cell deathChemistryCancer cellPhotosensitizerMetastasisPhotodynamic therapyBiophysicsDrug deliveryProgrammed cell deathCancerNanotechnologyMaterials scienceApoptosisMedicineBiochemistryBiologyPhotochemistryOrganic chemistryInternal medicineNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesUltrasound and Hyperthermia Applications