Targeted destruction of cancer stem cells using multifunctional magnetic nanoparticles that enable combined hyperthermia and chemotherapy
Dandan Liu, Yingcai Hong, Yaping Li, Chong Hu, Tak-Chun Yip, Wai-Kin Yu, Yu Zhu, Chi‐Chun Fong, Weimao Wang, Siu‐Kie Au, Shubin Wang, Mengsu Yang
Abstract
With good biocompatibility and targeting capability, the nanodrug delivery system may offer a promising clinical platform for the combined thermotherapy and chemotherapy. This work demonstrated the feasibility of developing multifunctional nanomedicine targeting CSCs for effective cancer treatment.
Topics & Concepts
In vivoCancer stem cellCancer researchNanomedicineMetastasisChemotherapyLung cancerMedicineIn vitroCancerCancer cellMaterials sciencePathologyChemistryNanotechnologyBiologyInternal medicineNanoparticleBiotechnologyBiochemistryCancer Cells and MetastasisMicrofluidic and Bio-sensing TechnologiesNanoparticle-Based Drug Delivery