Thermoneutral synthesis of spiro-1,4-cyclohexadienes by visible-light-driven dearomatization of benzylmalonates
Quanqing Zhao, Julia Rehbein, Oliver Reiser
Abstract
No preactivation or coupling to high-energy reagents is required for the dearomative coupling of benzylmalonates and acetylenes, although the transformation has no significant thermodynamic driving force.
Topics & Concepts
ChemistryOrganic chemistryRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques