USP14-mediated deubiquitination of SIRT1 in macrophage promotes fatty acid oxidation amplification and M2 phenotype polarization
Fei He, Yifei Chen, Dalin He, Shuixiang He
Topics & Concepts
Macrophage polarizationTumor microenvironmentCancerCancer researchCancer cellPhenotypeMalignancyMacrophageM2 MacrophageLipid metabolismImmune systemImmunophenotypingFatty acidImmunosurveillanceBiologyApoptosisChemistryImmunologyMedicineBiochemistryPathologyAntigenIn vitroGeneGeneticsAutophagy in Disease and TherapyImmune cells in cancerCancer, Hypoxia, and Metabolism