Two new bioactive secondary metabolites from the endophytic fungus <i>Talaromyces assiutensis</i> JTY2
Yingli Li, Ji‐Ling Yi, Jin Cai, Xue‐Ming Zhou, Li Chen, Xin Zhuo, Xin-Yi Lai
Abstract
One new lactone derivative helicascolide F (1), one new pyrrolidine derivative talaromydine (2), along with six known compounds (3–8) were isolated from the fungus Talaromyces assiutensis JTY2. The structure of the new compounds 1 and 2 was determined by 1D and 2D NMR as well as by HRESIMS. The inhibitory activity of all compounds against six phytopathogenic fungi and three cancer cell lines was evaluated.
Topics & Concepts
FungusStereochemistryChemistryCancer cell linesTwo-dimensional nuclear magnetic resonance spectroscopyDerivative (finance)BotanyBiologyCancer cellCancerGeneticsEconomicsFinancial economicsMicrobial Natural Products and BiosynthesisFungal Biology and ApplicationsPlant Pathogens and Fungal Diseases