Polysaccharide isolated from<i> Grifola frondosa</i> eliminates myeloid-derived suppressor cells and inhibits tumor growth by enhancing T cells responses
Xiangmin Li, Qinzhao Ruan, Weining Yang, Huixiang Tian, Nan Wu, Javeria Qadir, Juan Wang, Huiping Hu, Yuanchao Liu, Manjun Cai, Burton B. Yang, Yizhen Xie, Qingping Wu
Abstract
T cells and inhibiting tumor growth. This study introduces a promising therapeutic agent for breast cancer.
Topics & Concepts
Grifola frondosaMyeloid-derived Suppressor CellCancer researchDownregulation and upregulationCD8SpleenBone marrowImmune systemImmunologyTumor microenvironmentCancerCytotoxic T cellBiologyMedicineSuppressorPolysaccharideInternal medicineIn vitroGeneBiochemistryImmune cells in cancerCancer Cells and MetastasisImmune Response and Inflammation