A water-soluble cationic [2]biphenyl-extended pillar[6]arene: synthesis, host–guest interaction with hemin and application in chemodynamic/photodynamic cancer therapy
Yan Cai, Yue Zhang, Xufeng Liang, Chunlin Deng, Jianxia Zhang, Haotian Wang, Hui Duan, Yong Yao
Abstract
) was designed and synthesized successfully. It could form a stable 1 : 1 complex with hemin, thereby enhancing the stability of hemin in water, and can be further applied in cancer CDT and PDT.
Topics & Concepts
Cationic polymerizationPillarBiphenylPhotodynamic therapyHeminChemistryHost (biology)Cancer therapyCancerCombinatorial chemistryPhotochemistryPolymer chemistryBiochemistryOrganic chemistryBiologyStructural engineeringGeneticsEnzymeHemeEcologyEngineeringSupramolecular Chemistry and ComplexesPorphyrin and Phthalocyanine ChemistryLanthanide and Transition Metal Complexes