Staying tuned for post-COVID-19 syndrome: looking for new research to sniff out.
Christian Barbato, Maria Grazia Di Certo, Francesca Gabanella, Carla Petrella, Marco Fiore, Claudio Passananti, Andrea Colizza, Luca Cavalcanti, Massimo Ralli, Allison Greco, Marco de Vincentiis, Antonio Minni
Abstract
Post-COVID-19 syndrome was defined as a persistent and protracted illness, which follows acute COVID-19 infection. This condition continues for more than 12 weeks and cannot be attributed to other clinical situations. Researchers and clinicians are allied in unraveling the molecular pathogenetic mechanisms and the clinical development of this unexpected SARS-CoV-2 infectious evolution. Anosmia, dysgeusia, fatigue, dyspnea, and 'brain fog' are common symptoms observed in the Post-COVID-19 syndrome, depicting a multiorgan involvement associated with injuries involving mainly cardiovascular, pulmonary, musculoskeletal, and neuropsychiatric systems. This commentary analyzes the state of the art of Post-COVID-19 interdisciplinary studies, confirming that we are facing a truly intricate biomedicine story.