Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells
Jingjing Wang, Qi Su, Qing Wu, Kun Chen, Asmat Ullah, Mohsin Ahmad Ghauri, Yanmin Zhang
Topics & Concepts
MitophagyAutophagyApoptosisReactive oxygen speciesCancer researchChemistrySanguinarineCell biologyCathepsin DHepatocellular carcinomaCancer cellBiologyCancerBiochemistryGeneticsStereochemistryEnzymeAlkaloidAutophagy in Disease and TherapyCalcium signaling and nucleotide metabolismGinseng Biological Effects and Applications