An evolved artificial radical cyclase enables the construction of bicyclic terpenoid scaffolds via an H-atom transfer pathway
Dongping Chen, Xiang Zhang, Anastassia A. Vorobieva, Ryo Tachibana, Alina Stein, Roman P. Jakob, Zhi Zou, Damian Alexander Graf, Ang Li, Timm Maier, Bruno E. Correia, Thomas R. Ward
Topics & Concepts
ChemistryBicyclic moleculeTerpenoidElectron transferHydrogen atomStereochemistryCombinatorial chemistryPhotochemistryOrganic chemistryGroup (periodic table)Plant biochemistry and biosynthesisMicrobial Natural Products and BiosynthesisOxidative Organic Chemistry Reactions