Novel quinazolinone Derivatives: Design, synthesis and in vivo evaluation as potential agents targeting Alzheimer disease
Hadeer K. Moftah, Mai H. A. Mousa, Eman Z. Elrazaz, Ahmed S. Kamel, Deena S. Lasheen, Hanan H. Georgey
Topics & Concepts
AcetylcholinesteraseDonepezilChemistryQuinazolinoneNeuroprotectionIn vivoPharmacologyAchéCholinesteraseDocking (animal)DementiaBiochemistryMedicineDiseaseEnzymeInternal medicineStereochemistryBiologyNursingBiotechnologyCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsPhenothiazines and Benzothiazines Synthesis and Activities