Epitope prime editing shields hematopoietic cells from CD123 immunotherapy for acute myeloid leukemia
Rui-Jin Ji, Guohua Cao, Weiqiang Zhao, Mu-Yao Wang, Pan Gao, Yizhou Zhang, Xuebin Wang, Hou-Yuan Qiu, Di-Di Chen, Xiao-Han Tong, Min Duan, Hao Yin, Ying Zhang, Ying Zhang, Ying Zhang
Topics & Concepts
BiologyInterleukin-3 receptorMyeloid leukemiaEpitopeMyeloidImmunologyImmunotherapyHaematopoiesisLeukemiaCancer researchMyeloid cellsVirologyStem cellAntigenCell biologyImmune systemCRISPR and Genetic EngineeringCAR-T cell therapy researchT-cell and B-cell Immunology