Neuroprotective effects of roflumilast against quinolinic acid-induced rat model of Huntington’s disease through inhibition of NF-κB mediated neuroinflammatory markers and activation of cAMP/CREB/BDNF signaling pathway
Priyanka Saroj, Yashika Bansal, Raghunath Singh, Ansab Akhtar, Rupinder Kaur Sodhi, Mahendra Bishnoi, Sangeeta Pilkhwal Sah, Anurag Kuhad
Topics & Concepts
Quinolinic acidRoflumilastCREBNeuroprotectionPharmacologyNF-κBChemistryNeuroinflammationNFKB1Signal transductionMedicineNeuroscienceInflammationImmunologyBiologyInternal medicineBiochemistryTranscription factorCOPDTryptophanAmino acidGeneGenetic Neurodegenerative DiseasesMitochondrial Function and PathologyNeuroscience and Neuropharmacology Research