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USP18 mitigates lipopolysaccharide-induced oxidative stress and inflammation in human pulmonary microvascular endothelial cells through the TLR4/NF-κB/ROS signaling

Zeyu Jiang, Jiang Shen, Jie Ding, Yan Yuan, Lulu Gao, Zhuocheng Yang, Xin Zhao

2021Toxicology in Vitro29 citationsDOI

Topics & Concepts

Oxidative stressTLR4InflammationLipopolysaccharideDownregulation and upregulationReactive oxygen speciesSignal transductionChemistryCancer researchImmunologyBiologyPharmacologyCell biologyGeneBiochemistryInflammasome and immune disordersImmune Response and InflammationHeme Oxygenase-1 and Carbon Monoxide
USP18 mitigates lipopolysaccharide-induced oxidative stress and inflammation in human pulmonary microvascular endothelial cells through the TLR4/NF-κB/ROS signaling | Litcius