Multi-omics reveals that 5-O-methylvisammioside prevention acute liver injury in mice by regulating the TNF/MAPK/NF-κB/arachidonic acid pathway
Tingwen Zhang, Yue Zhong, Yan Shi, Chengcheng Feng, Lu Xu, Zheng Chen, Xin Sun, Xin Sun, Yan Zhao, Xialin Sun, Xialin Sun
Topics & Concepts
TranscriptomeLiver injuryArachidonic acidPharmacologyTumor necrosis factor alphaChemistryMAPK/ERK pathwayTLR4NF-κBProinflammatory cytokineAcetaminophenSignal transductionInflammationBiochemistryBiologyGene expressionGeneImmunologyEnzymeDrug-Induced Hepatotoxicity and ProtectionLiver physiology and pathologyInflammasome and immune disorders