Pharmacology and Mechanism of Action of HSK16149, a Selective Ligand of α2δ Subunit of Voltage-Gated Calcium Channel with Analgesic Activity in Animal Models of Chronic Pain
Xiaoli Gou, Xiaojuan Yu, Dongdong Bai, Bowei Tan, Pingfeng Cao, Meilin Qian, Xiaoxiao Zheng, Lei Chen, Zongjun Shi, Yao Li, Fei Ye, Yong Liang, Jia Ni, Fei Ye, Yong Liang, Jia Ni
Topics & Concepts
AnalgesicCalcium channelPharmacologyMechanism of actionVoltage-dependent calcium channelChronic painN-type calcium channelMechanism (biology)ChemistryProtein subunitCalciumLigand (biochemistry)MedicineAnesthesiaT-type calcium channelReceptorInternal medicineIn vitroBiochemistryPhysical therapyEpistemologyPhilosophyGenePain Mechanisms and TreatmentsCholinesterase and Neurodegenerative DiseasesIon channel regulation and function