Discovery of novel celastrol-triazole derivatives with Hsp90-Cdc37 disruption to induce tumor cell apoptosis
Na Li, Cheng Chen, Huiting Zhu, Zhixian Shi, Jianbo Sun, Li Chen
Topics & Concepts
ChemistryCelastrolApoptosisHsp90Cell growthCysteineCell cultureCancer researchBiochemistryEnzymeHeat shock proteinBiologyGeneticsGeneNatural Compounds in Disease TreatmentNatural product bioactivities and synthesisCancer Mechanisms and Therapy