Wnt-activating human skin organoid model of atopic dermatitis induced by Staphylococcus aureus and its protective effects by Cutibacterium acnes
Song-Yi Jung, Hyun Ju You, Minji Kim, GwangPyo Ko, Seunghee Lee, Kyung‐Sun Kang
Abstract
had a protective effect on SA-infected organoids. Thus, this ALI-skin organoid platform may be a useful tool for modeling human skin diseases and evaluating the efficacy of novel therapeutics.
Topics & Concepts
OrganoidAtopic dermatitisStaphylococcus aureusHuman skinCartilageImmunologyWnt signaling pathwayMicrobiologyMedicineBiologyCell biologyBacteriaAnatomySignal transductionGeneticsDermatology and Skin DiseasesAllergic Rhinitis and SensitizationAdvancements in Transdermal Drug Delivery