Chiral <sup>1</sup>H NMR Analysis of Carbonyl Compounds Enabled by Cationic Cobalt Complex
Sumin Jang, Hyunwoo Kim
Abstract
We report a newly prepared cationic cobalt(III) complex as a general and efficient chiral solvating agent that discriminates carbonyl compounds including esters, amides, ketones, and aldehydes. This cobalt(III) complex was further utilized to directly analyze both the conversion and the enantiomeric excess at once in the asymmetric fluorination.
Topics & Concepts
Cationic polymerizationChemistryCobaltEnantiomerEnantiomeric excessOrganic chemistryCombinatorial chemistryEnantioselective synthesisCatalysisMolecular spectroscopy and chiralityAnalytical Chemistry and ChromatographyAsymmetric Synthesis and Catalysis