Involvement of acetylation of ATG4B in controlling autophagy induction
Haojun Xiong, Liangbo Sun, Jiqin Lian, Fengtian He
Abstract
) mice. Collectively, our results have revealed the acetylation-mediated regulation of ATG4B cysteine protease activity in autophagy initiation in response to nutritional deficiency.
Topics & Concepts
SIRT2AutophagyAcetylationBiologyUbiquitinCell biologyCysteine proteasePhosphorylationSequestosome 1BiochemistryProteaseSirtuinGeneEnzymeApoptosisAutophagy in Disease and TherapySirtuins and Resveratrol in MedicineCalcium signaling and nucleotide metabolism