Comparison of the gut microbiome composition among individuals with acute or long-standing spinal cord injury vs. able-bodied controls
Jia Li, William Van Der Pol, Mualla Eraslan, Amie McLain, Hatice Çetin, Barış Çetin, Casey D. Morrow, Tiffany L. Carson, Ceren Yarar‐Fisher
Abstract
: Our results revealed differences in the gut microbiome composition among groups. Compared to the AB controls, the SCI groups demonstrated microbiome profiles that shared features linked to metabolic syndrome, inflammation-related bowel disorders, depressive disorders, or antibiotics use, whereas the L-SCI group's microbiome included features linked to reduced physical activity compared to the A-SCI and AB controls. Our results provided preliminary data and a scientific foundation for future studies investigating the impact of the gut microbiome composition on long-term health in individuals with SCI.
Topics & Concepts
MedicineSpinal cord injuryMicrobiomeGut microbiomeSpinal cordPhysical therapyPhysical medicine and rehabilitationGut floraBioinformaticsImmunologyBiologyPsychiatryGut microbiota and healthSpinal Cord Injury ResearchPediatric Pain Management Techniques