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Synthesis and study of the biological activity of thiourea-containing amiridine derivatives as potential multi-target drugs for the treatment of Alzheimer’s disease

Галина Ф. Махаева, Alexey N. Proshin, N. V. Kovaleva, Елена В. Рудакова, Natalia P. Boltneva, Sofya V. Lushchekina, T. Yu. Astakhova, И. В. Серков, I. P. Kalashnikova, С. О. Бачурин

2022Russian Chemical Bulletin21 citationsDOI

Topics & Concepts

ChemistryThioureaButyrylcholinesteraseAntioxidantDrugCombinatorial chemistryDonepezilAcetylcholinesteraseDocking (animal)PharmacologyAchéOrganic chemistryDiseaseDementiaEnzymeNursingMedicinePathologyCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsSynthesis and biological activity
Synthesis and study of the biological activity of thiourea-containing amiridine derivatives as potential multi-target drugs for the treatment of Alzheimer’s disease | Litcius