Evolutionary and Functional Analysis of Coagulase Positivity among the Staphylococci
Amy C. Pickering, Gonzalo Yebra, Xiangyu Gong, Mariya I. Goncheva, Bryan A. Wee, Alison C. MacFadyen, Lukas F. Muehlbauer, Joana Alves, Robyn A. Cartwright, Gavin K. Paterson, J. Ross Fitzgerald
Abstract
has undergone adaptive diversification to facilitate host-specific functionality. Our findings provide important insights into the evolution of pathogenicity among the staphylococci and the genetic basis for a defining diagnostic phenotype.
Topics & Concepts
CoagulaseBiologyMicrobiologyStaphylococcus aureusStaphylococcusGeneticsBacteriaAntimicrobial Resistance in StaphylococcusBacterial biofilms and quorum sensing