Isolation and identification of an α-glucosidase inhibitory peptide from extruded soybean protein and its hypoglycemic activity in T2DM mice
Wenhui Li, Xiaohang Fu, Tianyu Zhang, He Li, Tianpeng Chen, Xinqi Liu
Abstract
The α-glucosidase inhibitory peptide LLRPPK was isolated from ESPro1 (160 °C, 30 r min −1 ) in vitro . Meanwhile, ESPro1 was shown to regulate glucose and lipid metabolism, and attenuate liver and pancreatic injury in T2DM mice in vivo .
Topics & Concepts
ChemistryIn vivoMalondialdehydeInsulin resistanceBiochemistryGlutathione peroxidaseGlutathioneAntioxidantCholesterolSuperoxide dismutaseEndocrinologyInternal medicinePharmacologyInsulinEnzymeBiologyMedicineBiotechnologyProtein Hydrolysis and Bioactive PeptidesProteins in Food SystemsMeat and Animal Product Quality