Baicalin down-regulating hepatitis B virus transcription depends on the liver-specific HNF4α-HNF1α axis
Chengjie Xia, Wenyi Tang, Ping Geng, Haiyan Zhu, Wei Zhou, Hai Huang, Pei Zhou, Xunlong Shi
Topics & Concepts
TransactivationHepatocyte nuclear factorsChromatin immunoprecipitationHepatocyte nuclear factor 4Hepatitis B virusSmall hairpin RNATranscription factorChemistryDownregulation and upregulationImmunoprecipitationTranscription (linguistics)EntecavirHepatocyteTransfectionHepatitis B virus PRE betaVirologyMolecular biologyCell biologyBiologyPromoterGene knockdownGeneGene expressionVirusBiochemistryIn vitroHepatitis B virus DNA polymeraseNuclear receptorLamivudinePhilosophyLinguisticsHepatitis B Virus StudiesLiver Disease Diagnosis and TreatmentCell death mechanisms and regulation