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Additional Og-Typing PCR Techniques Targeting Escherichia coli-Novel and <i>Shigella</i> -Unique O-Antigen Biosynthesis Gene Clusters

Atsushi Iguchi, Hironobu Nishii, Kazuko Seto, Jiro Mitobe, Kenichi Lee, Noriko Konishi, Hiromi Obata, Taisei Kikuchi, Sunao Iyoda

2020Journal of Clinical Microbiology15 citationsDOIOpen Access PDF

Abstract

The O-serogrouping of pathogenic Escherichia coli is a standard method for subtyping strains for epidemiological studies and controls. O-serogroup diversification shows a strong association with the genetic diversity in some O-antigen biosynthesis gene clusters. Through genomic studies, in addition to the types of O-antigen biosynthesis gene clusters (Og-types) from conventional O-serogroup strains, a number of novel Og-types have been found in E. coli isolates.

Topics & Concepts

SubtypingBiologyEscherichia coliTypingShigellaGeneGene clusterAntigenMicrobiologyGeneticsEscherichiaProgramming languageComputer scienceEscherichia coli research studiesViral gastroenteritis research and epidemiologyBacteriophages and microbial interactions