Evaluation of Modulatory Activities of Lactobacillus crispatus Strains in the Context of the Vaginal Microbiota
Chiara Argentini, Federico Fontana, Giulia Alessandri, Gabriele Andrea Lugli, Leonardo Mancabelli, Maria Cristina Ossiprandi, Douwe van Sinderen, Marco Ventura, Christian Milani, Francesca Turroni
Abstract
experiments followed by genetic analyses of the mechanisms used by L. crispatus in colonizing the vaginal ecological niche, particularly in the production of different antimicrobial compounds, were evaluated, highlighting some intriguing novel aspects concerning the genetic variability of this species. Our results indicate that this species has adapted to its niche and may still undergo adaptation to enhance its competitiveness for niche colonization.
Topics & Concepts
Lactobacillus crispatusBiologyLactobacillusContext (archaeology)Lactobacillus gasseriMicrobiologyBacteriaGeneticsPaleontologyReproductive tract infections researchGut microbiota and healthProbiotics and Fermented Foods