AKT constitutes a signal-promoted alternative exon-junction complex that regulates nonsense-mediated mRNA decay
Hana Cho, Elizabeth Abshire, Maximilian W. Popp, Christoph Pröschel, Joshua L. Schwartz, G Yeo, Lynne E. Maquat
Topics & Concepts
Nonsense-mediated decayBiologyProtein kinase BCell biologyPI3K/AKT/mTOR pathwayExonRNA Helicase APhosphorylationEffectorSignal transductionDownregulation and upregulationHelicaseRNAGeneticsGeneRNA splicingRNA Research and SplicingGenetics and Neurodevelopmental DisordersDNA Repair Mechanisms