Semi-synthesis and biological evaluation of flavone hybrids as multifunctional agents for the potential treatment of Alzheimer's disease
Shao-Chun Shi, Huibin Wang, Jian Wang, Yvxi Wang, Xiao-Bian Xue, Zi‐Lin Hou, Guo‐Dong Yao, Xiao‐Xiao Huang, Hongwei Zhao, Qingbo Liu, Shao‐Jiang Song
Topics & Concepts
ChemistryNeuroprotectionIn vitroIC50AchéSH-SY5YInhibitory postsynaptic potentialBiochemistryLead compoundPharmacologyAmyloid (mycology)FlavonoidEnzymeAcetylcholinesteraseNeuroblastomaAntioxidantNeuroscienceCell cultureBiologyGeneticsInorganic chemistryCholinesterase and Neurodegenerative DiseasesAlzheimer's disease research and treatmentsMedicinal Plants and Neuroprotection