Decoding ischemic stroke: Perspectives on the endoplasmic reticulum, mitochondria, and their crosstalk
Chuxin Zhang, Xin Lan, Qingguo Wang, Yuxiao Zheng, Jialin Cheng, Jinhua Han, Changxiang Li, Fafeng Cheng, Xueqian Wang
Abstract
destabilization homeostasis, ER stress, oxidative stress, disordered mitochondrial quality control, and mitochondrial transfer. Additionally, this article highlights the functional interaction between the ER and mitochondria, as well as the mitochondrial-ER contacts (MERCs) that structurally connect mitochondria and the ER, aiming to provide ideas and references for the research and treatment of IS.
Topics & Concepts
Endoplasmic reticulumCrosstalkMitochondrionCell biologyIschemic strokeDecoding methodsIschemiaBiologyNeuroscienceMedicineComputer scienceInternal medicineTelecommunicationsEngineeringElectronic engineeringMitochondrial Function and PathologyNeuroscience and Neuropharmacology ResearchGenetic Neurodegenerative Diseases